4/18/2023 0 Comments Stem cell treatment msOver years, the disease can worsen and shift to a progressive form that may also include relapses. Incomplete recovery from relapses often leads to increasing disability. The most common form of the disease is relapsing-remitting MS, which is characterized by periods of mild or no symptoms interspersed with symptom flare-ups, or relapses. Symptoms of the disease vary widely and may include motor and speech difficulties, weakness, fatigue and chronic pain. It is estimated that MS affects more than 2.3 million people worldwide, mostly women, including more than one million people in the United States. However, we need to be certain that the benefits of this form of treatment outweigh its serious risks.” “AHSCT has the potential to halt the progress of relapsing MS, eliminate the need for a person to take lifelong medication, and allow the body to partially regain function. “For many people with MS - a chronic, debilitating, unpredictable and currently incurable disease - daily life can be a challenge,” said NIAID Director Anthony S. This form of treatment is called autologous hematopoietic stem cell transplantation, or AHSCT. These cells repopulate the immune system, allowing it to reset itself so that the new immune cells no longer attack the central nervous system. Some of the person’s own blood-forming stem cells, which were extracted before treatment, are then infused back into the individual. The experimental treatment involves using a mixture of four chemical agents to remove these immune cells. MS is an autoimmune disease in which a person’s own immune cells attack the central nervous system. NIAIDĪ clinical trial has begun testing an experimental stem cell treatment against the best available biologic therapies for severe forms of relapsing multiple sclerosis (MS). The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, will compare the safety, efficacy and cost-effectiveness of the two therapeutic approaches. In multiple sclerosis, certain kinds of T cells are involved in the immune system’s attack on the central nervous system. Scanning electron micrograph of a human T cell from the immune system of a healthy donor.
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